Table 2.
Stem cells delivery in peripheral nerve regeneration.
| Methods | Application | Advantage and Disadvantage | References |
|---|---|---|---|
| Micro injection | Traumatic both to the stem cells and delicate intra-neural architecture, abnormal cell distribution | Pang [116] | |
| Conduit | Natural conduits or artificial | Difficult for cell delivery | Nijhuis [25] Costa [123] Yang [124] Carrier-Ruiz [27] Wakao [125] |
| Conduit + ECM | Collagen, fibirin | Good cell distribution, lack of 3-D construction | Pereira [126] di Summa [127] |
| Conduit + internal | Beneficial for axonal guidance | Wakao [125] Hu [128] Gu [129] | |
| 3-D print | Customization, good cell distribution | Weightman [121] Hu [122] Tse [118] |