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. 2017 Jan 10;18(1):123. doi: 10.3390/ijms18010123

Figure 2.

Figure 2

Multivariate receiver operating characteristic (ROC) curves representing correlations between concentrations of CA125, HE4, osteopontin, follistatin, PDGF-AB/BB in differentiating non-malignant ovarian tumours vs. ovarian cancer; Models 2 and 3 are mostly based on CA125, HE4 and osteopontin; Model 2 allowed to obtain an AUC of 0.936, while the model 3, in which osteopontin is more frequently selected, increased the AUC to 0.951; The use of additional angiogenesis markers (models 4 and 5) did not improve the diagnostic accuracy.