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. 2017 Jan 11;18(1):124. doi: 10.3390/ijms18010124

Figure 1.

Figure 1

Figure 1

Expression profile of hepatic fatty acid metabolism genes. Animals from the SWE, SHAE, and SAE groups were treated daily with corresponding extracts at a dose of 2 g/kg body weight (Per os). A, B, C, D, E and F are expression profiles of the CPT1A, MCAT, ACACA, ACSL1, FASN and FABP genes, respectively. RNA was isolated from the animals’ livers and cDNA was prepared. cDNA was analyzed for the modulation of fatty acid metabolism genes. Results are represented as mean ± SE (n = 3 for each group and the reactions were performed in duplicate). Comparisons between the control group and experimental groups were performed by Dunnett’s multiple comparison test. (* p ≤ 0.05, ** p ≤ 0.01, when compared with thehealthy control group; # p ≤ 0.05, ## p ≤ 0.01, when compared with the NIC-STZ control group; + p ≤ 0.05, ++ p ≤ 0.01, when compared with the MET-treated control group). HC: Healthy control, NIC-STZ: NIC-STZ treated control, MET: Metformin-treated control, SWE: Strawberry aqueous extract, SHAE: Strawberry hydro-alcoholic extract, SAE: Strawberry alcohol extract, CPT1A: Carnitine Palmitoyltransferase 1A, MCAT: Malonyl-CoA: ACP Acyltransferase, ACACA: Acetyl-CoA Carboxylase α, ACSL1: Acyl-CoA Synthetase Long-chain family member 1, FASN: Fatty Acid Synthase, FABP: Fatty Acid Binding Protein.