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. 2017 Jan 18;18(1):184. doi: 10.3390/ijms18010184

Figure 1.

Figure 1

Neuroprotective effect of CSP-1103, but not ibuprofen, in cortical neurons exposed to oxygen glucose deprivation (OGD). (A) Cortical neurons were exposed to 3 h OGD and neuronal death was assessed after 24 h recovery by the lactate dehydrogenase (LDH) assay. CSP-1103, added after the OGD period, increased the survival of injured neurons at different concentrations (1 and 3 μM); (B) Lack of neuroprotective effect of ibuprofen in cortical neurons exposed to 3 h OGD. Different doses of ibuprofen were added after OGD and the neuronal death was measured by the LDH assay 24 h later. Values are expressed as percentage of the LDH released by the cells exposed to OGD. * p < 0.05, ** p < 0.01 vs. OGD value. +, presence of OGD; −, absence of OGD or treatment.