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. 2016 Oct 28;12(2):106–119. doi: 10.1002/cmdc.201600441

Scheme 1.

Scheme 1

Synthesis of compound 6. Reagents and conditions: a) (3‐fluorobenzyl)magnesium bromide, THF, RT, 2 h, 66.5 %; b) Dess–Martin periodinane, CH2Cl2, RT, 3 h, 94.8 %; c) substituted phenylmagnesium bromide, THF, RT, 2 h, 56.1–86.9 %.