Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
In vitro antitubercular activity of series 3 compounds.[a]
|
||||||
|---|---|---|---|---|---|---|
| Compd | R | MIC | CC50 [b] | |||
| μg mL−1 | μm | μg mL−1 | μm | |||
| 22 |
|
4.0 | 10.0 | 11 | 27.5 | |
| 23 |
|
2.0 | 4.3 | 4.4 | 9.5 | |
| 24 |
|
1.8 | 4.1 | 10 | 22.5 | |
[a] Reference compound: bedaquiline MIC=0.060 μg mL−1 (0.1 μm). [b] Concentration at which the growth of Vero cells is inhibited by 50 %.
