5. Review secondary outcomes ‐ platelet and red cell transfusions.
| Study ID | Number of PLTs transfused per participant | Number of participant‐days with PLT transfusions | Proportion of participant‐days with RBC transfusions | Interval between PLT transfusions (mean & SD)(days) | Number of PLT units per transfusion (mean & SD) (units) | Nmber of PLT transfusion per participant |
| RCTs | ||||||
| De Zern 2016 | NR | NR | NR | NR | NR |
Restrictive: median:9 (IQR: 5.5 to 12.5) Liberal; median: 9 (IQR: 7 to 12) |
| Robitaille 2013 | NR | NR | NR | NR | NR | NR |
| Webert 2008 |
Restrictive: 26/29 from study entry, 26 from when target Hb reached Liberal: 27/31 from study entry; 26 from when target Hb reached |
Restrictive: 124 from study entry; 122 from Hb 80 g/L to 100 g/L Liberal: 0.265 from study entry; 0.283 from when Hb > 120 g/L |
Restrictive: 0.249 from study entry; 0.261 from when Hb 8‐10 Liberal: 0.265 from study entry; 0.283 from when Hb > 12 [RR 1.06; 95% CI 0.74 to 1.52] [RR 1.02: 95% CI 0.73 to 1.44; once study Hb threshold reached]a |
NR | NR | NR |
| NRS | ||||||
| Jansen 2004 |
Restrictive: Mean 7.5 (SD 3.8); median 7 (SE 0.6); range 2 to 18 Liberal: Mean 8.5 (SD 4.9); median 7 (SE 0.7); range 2 to 30 P > 0.05 |
NR | NR |
Restrictive: 4 days (No SD) Liberal: 3.8 days (No SD) |
Restrictive: Mean 1.1 (SD 0.4); median 1 (SE 0.03); range 1 to 4 Liberal: Mean 1.2 (SD 0.5); Median 1 (SE 0.03); range 1 to 4 |
NR |
aData analysed by study authors, reported as relative risks derived from Cox regression models.
IQR = Interquartile range