Table 2. Subject characteristics.
| Healthy subjects (n = 30) | COPD (n = 32) | IPF (n = 15) | |
|---|---|---|---|
| Age, yrs | 55(9) | 63(9)*** | 72(9)***° |
| Gender (M/F) | 11/19 | 24/8 | 12/3 |
| Height, cm | 169(8) | 171(9) | 170(12) |
| Weight, Kg | 72(12) | 71(17) | 76(13) |
| BMI, Kg/m2 | 25(3) | 24(4) | 26(3) |
| Smokers (Never/ex/Current), n | 13/8/9 | 1/17/14 | 2/10/3 |
| pack-yr | 9(13) | 47(32)*** | 33(24)** |
| FEV1%pred | 111(11) | 49(16) | 69(15) |
| FVC %pred | 114(15) | 81(14) | 69(16) |
| FEV1/FVC % | 80(4) | 48(10) | 76(11) |
| TLC, %pred | nd | 115(19) | 68(14) |
| RV, %pred | nd | 192(58) | 65(49)°°° |
| DLCO %pred | nd | 56(14) | 36(16)° |
| KCO %pred | nd | 76(20) | 59(16) |
| ICS (yes/no) | 0/30 | 12/20 | 3/12 |
| OCS (yes/no) | 0/30 | 2/30 | 2/13 |
Data are expressed as mean (SD).
* p < 0.05 compared to healthy subjects.
** p < 0.001 compared to healthy subjects.
*** p < 0.0001 compared to healthy subjects.
° p < 0.05 compared to COPD.
°° p < 0.001 compared to COPD.
°°° p < 0.0001 compared to COPD.
FEV1: forced expiratory volume in one second; FVC: forced vital capacity; TLC: total lung capacity; RV: residual volume; DLCO: diffusion capacity of CO in the lung; ICS: inhaled corticosteroid; OCS: oral corticosteroid.