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. 2017 Jan 30;8(1):e0001. doi: 10.5041/RMMJ.10276

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© 2017 Faria et al

This is an open-access article. All its content, except where otherwise noted, is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Diffuse or focal NP presentations may arise (1) directly as a result of autoimmune mechanisms (primary NPSLE), in which case treatment should target the most relevant pathologic mechanism (anticoagulation in aPL-associated thrombosis or immunosuppression in antibody-mediated diffuse damage); (2) secondary to complications of the disease or treatment (secondary NPSLE), which may require treatment such as antibiotic therapy for bacterial infection; and (3) finally as a consequence of NP events related to SLE, which may have specific treatment.

HCQ, hydroxychloroquine.