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. 2016 Oct 3;9(1):46–58. doi: 10.1177/1758834016670555

Figure 1.

Figure 1.

BRAF mutations are found in exons 11 and 15, which are both within the kinase domain (yellow bar). The conserved glycine motif (G-loop) in exon 11 and the activation segment in exon 15 are indicated with a grey bar. All BRAF mutations are within these two areas.