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. 2017 Jan 1;9(1):1759091416689020. doi: 10.1177/1759091416689020

Figure 4.

Figure 4.

Loss of aggrecan-containing PNNs in collagen XIX-deficient cerebral cortex. Aggrecan (Acan)-immunolabeled PNNs in P56 wild-type (Ctl; (a), (d), and (g)) and col19a1−/− mutant (KO; (b), (e), and (h)). Images depict Acan-rich PNNs in primary visual cortex (vCtx; (a) and (b)), prefrontal cortex (pfCtx; (d) and (e)), and motor cortex (mCtx; (g) and (h)). Quantification of Acan-immunolabeled PNNs in P56 WT and KO vCtx (c), pfCtx (f), and mCtx (i). Data represent means ± standard deviation (SD). * indicates differs from littermate WT by p < 0.05 by Student’s t-test. Scale bar in (h) = 25 µm for (a), (b), (d), (e), (g), and (h).