Table 3.
Multivariate analysis of factors influencing survival using a cox proportional hazards model.
| Characteristics | Male |
Female |
||
|---|---|---|---|---|
| Hazards ratio | p value | Hazards ratio | p value | |
| Age | ||||
| ⩽55 | 1 | 1 | ||
| >55 | 4.46 (3.95–5.87) | <0.05 | 2.9 (1.53–3.45) | <0.05 |
| Tumor size | ||||
| ⩽3 cm | 1 | 1 | ||
| >3 cm | 1.15 (0.92–1.44) | NS | 1.15 (0.80–1.65) | NS |
| Lymphovascular invasion | ||||
| No | 1 | 1 | ||
| Yes | 1.39 (0.99–1.99) | NS | 0.72 (0.35–1.32) | NS |
| Lymph node metastasis | ||||
| No | 1 | 1 | ||
| Yes | 1.34 (0.96–1.84) | NS | 3.33 (2.14–5.04) | <0.05 |
| Depth of invasion | ||||
| Mucosa | 1 | 1 | ||
| Submucosa | 1.35 (1.06–1.71) | <0.05 | 1.11 (0.78–1.72) | NS |
| Histology | ||||
| WD-TUB | 1 | 1 | ||
| MD-TUB | 0.73 (0.53–0.92) | <0.05 | 0.95 (0.54–1.69) | NS |
| PD-TUB | 0.83 (0.63–1.10) | NS | 1.01 (0.61–1.68) | NS |
| SRC | 0.50 (0.39–0.83) | <0.05 | 0.69 (0.37–3.45) | NS |
NS, nonspecific; MD-TUB, moderately differentiated tubular adenocarcinoma; PD-TUB, poorly differentiated tubular adenocarcinoma; SRC, signet ring cell carcinoma; WD-TUB, well-differentiated tubular adenocarcinoma.