Table 4.
Multivariate analysis of factors influencing survival using a cox proportional hazards model.
| Characteristics | ⩽ 55 years |
> 55 years |
||
|---|---|---|---|---|
| Hazards ratio | p value | Hazards ratio | p value | |
| Sex | ||||
| Male | 1 | 1 | ||
| Female | 1.03 (0.68–1.55) | NS | 0.54 (0.42–0.69) | <0.05 |
| Tumor size | ||||
| ⩽3 cm | 1 | 1 | ||
| >3 cm | 1.55 (1.03–2.28) | <0.05 | 1.02 (10.7–1.27) | NS |
| Lymphovascular invasion | ||||
| No | 1 | 1 | ||
| Yes | 1.12 (0.62–2.02) | NS | 1.17 (0.83–1.65) | NS |
| Lymph node metastasis | ||||
| No | 1 | 1 | ||
| Yes | 2.97 (1.86–4.75) | <0.05 | 1.45 (1.07–1.98) | <0.05 |
| Depth of invasion | ||||
| Mucosa | 1 | 1 | ||
| Submucosa | 1.43 (0.93–2.21) | NS | 1.26 (1.00–1.59) | NS |
| Histology | ||||
| WD-TUB | 1 | 1 | ||
| MD-TUB | 0.64 (0.34–1.20) | NS | 0.76 (0.58–0.99) | <0.05 |
| PD-TUB | 0.71 (0.40–1.27 | NS | 0.93 (0.71–1.22) | NS |
| SRC | 0.63 (0.32–1.55) | NS | 0.54 (0.42–0.69) | <0.05 |
NS, nonspecific; MD-TUB, moderately differentiated tubular adenocarcinoma; PD-TUB, poorly differentiated tubular adenocarcinoma; SRC, signet ring cell carcinoma; WD-TUB, well-differentiated tubular adenocarcinoma.