Skip to main content
. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Circ Cardiovasc Genet. 2017 Jan;10(1):e001404. doi: 10.1161/CIRCGENETICS.116.001404

Figure 2.

Figure 2

Effect of the rs10995 polymorphism on the blood pressure response of whites treated with thiazide diuretics in the PEAR and PEAR-2 studies. Blood pressure responses were adjusted for baseline blood pressure, age, gender, and PC1 and 2. P-values represented are for contrast of adjusted means between different genotype groups. Error bars represent standard error of the mean. *One sided p-value based on a one-sided hypothesis tested in the replication study. A)systolic blood pressure response to hydrochlorothiazide in the PEAR study. B)diastolic blood pressure response in the PEAR study. C)systolic blood pressure response to chlorthalidone in the PEAR-2 study. D)diastolic blood pressure response to chlorthalidone in the PEAR-2 study.