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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Nanomedicine. 2016 Aug 9;13(2):443–454. doi: 10.1016/j.nano.2016.07.015

Figure 6.

Figure 6

Distribution of IgG subclasses generated by immunization with nicotine vaccines. (A) IgG1; (B) IgG2a; (C) IgG2b; (D) IgG3. In the blank group, mice were injected with phosphate-buffered saline as the negative control. Comparisons among groups were analyzed by one-way ANOVA followed by Tukey's HSD test. Data are expressed as means ± SD. Significantly different compared to the Nic-KLH with alum groups: *p < 0.05, **p < 0.01, ***p < 0.001. Significantly different: #p < 0.05, ##p < 0.01.