Table 2.
Overview of treatment and tumor characteristics for the up-front transoral robotic surgery group (N = 56).
| Characteristic | Value (N = 56) | % |
|---|---|---|
| Subsite | ||
| Oropharynx | 46 | 82.1 |
| Base of tongue | 9 | |
| Tonsil | 32 | |
| Posterior wall | 1 | |
| Vallecula | 2 | |
| Glossotonsillar sulcus | 1 | |
| Retromolar trigone | 1 | |
| Supraglottic larynx | 5 | 8.9 |
| Epiglottis | 3 | |
| Aryepiglottic fold | 1 | |
| Unknown | 1 | |
| Hypopharynx (pyriform sinus) | 5 | 8.9 |
| Clinical tumor classification | ||
| cT0 Oropharynx | 1 | 1.8 |
| cT1 | 23 | 41.1 |
| Oropharynx | 17 | |
| Supraglottic larynx | 3 | |
| Hypopharynx | 3 | |
| cT2 | 27 | 48.2 |
| Oropharynx | 24 | |
| Supraglottic larynx | 2 | |
| Hypopharynx | 1 | |
| cT3 | 4 | 7.1 |
| Oropharynx | 3 | |
| Hypopharynx | 1 | |
| cT4a Oropharynx | 1 | 1.8 |
| Clinical nodal classification | ||
| cN0 | 18 | 32.1 |
| cN1 | 13 | 23.2 |
| cN2 | 25 | 44.6 |
| Neck dissection | ||
| Yes | 49 | 87.5 |
| Levels I–III | 4 | |
| Levels II–III | 1 | |
| Levels II–IV | 10 | |
| Levels I–IV | 4 | |
| Levels II–V | 10 | |
| Levels I–V | 20 | |
| No | 7 | 12.5 |
| Surgical margin status | ||
| Clear | 21 | 37.5 |
| Close (<5 mm) | 10 | 17.9 |
| Positive | 24 | 42.9 |
| Second primary in margin | 1 | 1.8 |
| Pathological tumor classification | ||
| pT1 | 24 | 42.9 |
| Oropharynx | 18 | |
| Supraglottic larynx | 3 | |
| Hypopharynx | 3 | |
| pT2 | 27 | 48.2 |
| Oropharynx | 25 | |
| Supraglottic larynx | 1 | |
| Hypopharynx | 1 | |
| pT3 | 2 | 3.6 |
| Oropharynx | 1 | |
| Hypopharynx | 1 | |
| pT4 | 2 | 3.6 |
| Oropharynx | 1 | |
| Hypopharynx | 1 | |
| pR2 (macroscopic residual tumor) (oropharynx) | 1 | 1.8 |
| Pathological nodal classification | ||
| pNx | 7 | 12.5 |
| pN0 | 15 | 26.8 |
| pN1 | 11 | 19.6 |
| pN2a | 7 | 12.5 |
| pN2b | 16 | 28.6 |
| pN2c | 0 | |
| Adjuvant treatment | ||
| No adjuvant treatment, follow-up | 13 | 23.2 |
| Radiotherapy | 26 | 46.4 |
| Chemoradiotherapy | 15 | 26.8 |
| Surgery (TLM) + radiotherapy | 1 | 1.8 |
| Undetermined (early death) | 1 | 1.8 |
TLM, transoral laser microsurgery.