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Plasma miRNAs are differentially regulated during early fibrosis in patients with chronic HBV and HCV infection. The plasma levels of miRNA-122, -150, -192, -21, -200b, and -92a were measured by real-time quantitative PCR, and obtained Ct levels were normalized by use of spiked-in cel-miRNA-39. The miRNA expression levels in plasma of F0/F1/F2 patients with chronic HBV and HCV infection were compared with healthy control subjects. ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001; ∗∗∗∗P < 0.0001.
