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. 2017 Feb 9;8:76. doi: 10.3389/fphys.2017.00076

Figure 2.

Figure 2

Role of 5-HT receptors and 5-HT transporter in 5-HT-induced O2_ increase in rat IPA. (A) Effect of a 5-HT2 receptor antagonist (ketanserin, 1 μM, dark gray column), a 5-HT1 receptor antagonist (GR127935, 1 μM, light gray column) or a 5-HT transporter antagonist (citalopram, 1 μM, hatched column) on the O2_ produced by 100 μM 5-HT. (B) α-methyl 5-HT 10 μM significantly increases O2_ levels in rat IPA. Data are expressed as mean ± SEM. * and ** indicate a significant difference with P < 0.05 and P < 0.01 respectively. n is the number of rats.