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. 2017 Feb 9;8:185. doi: 10.3389/fmicb.2017.00185

Table 4.

Comparison of the performances of the REBA-EAC assay versus sequence analysis for detecting β-lactamase genes in the 327 ESBL-phenotypically confirmed isolates.

Class of β-lactamase (no. of isolates) Type of β-lactamase gene Microorganism No. of isolates
REBA-EAC assay Sequence analysis
ESBL (382) CTX-M-1/2 CTX-M-1 E. coli 97
CTX-M-1/2 CTX-M-1 K. pneumoniae 3
CTX-M-1/2 CTX-M-1 K. oxytoca 1
CTX-M-1/2 CTX-M-1 E. aerogenes 1
CTX-M-9 CTX-M-9 E. coli 86
CTX-M-9 CTX-M-9 K. pneumoniae 49
CTX-M-9 CTX-M-9 P. mirabilis 4
CTX-M-9 CTX-M-9 E. cloacae 2
CTX-M-9 CTX-M-9 P. mirabilis 4
CTX-M-1/2 + CTX-M-9 CTX-M-1 + CTX-M-9 E. coli 2
CTX-M-1/2 + CTX-M-9 CTX-M-1 + CTX-M-9 K. pneumoniae 1
TEM TEM-3 K. pneumoniae 3
TEM TEM-22 E. coli 21
TEM TEM-22 K. pneumoniae 5
TEM TEM-46 E. coli 9
TEM TEM-46 K. pneumoniae 5
TEM TEM-52 E. coli 25
TEM TEM-52 K. pneumoniae 10
TEM TEM-66 E. coli 21
TEM TEM-66 K. pneumoniae 5
SHV SHV-2a K. pneumoniae 14
SHV SHV-5 K. pneumoniae 5
SHV SHV-12 K. pneumoniae 10
SHV SHV-12 K. oxytoca 2
AmpC β-lactamase (92) DHA DHA-1 K. pneumoniae 61
DHA DHA-23 K. pneumoniae 8
DHA DHA-15 K. pneumoniae 5
DHA DHA-3 K. pneumoniae 1
DHA DHA-1 E. coli 2
CMY-2-like CMY-2 K. pneumoniae 7
CMY-2-like CMY-2 E. coli 4
DHA+CMY-2-like DHA+CMY-2 K. pneumoniae 2
ACT ACT-1 E. coli 1
ACT ACT-1 E. aerogenes 1
Carbapenemase (6) NDM NDM-1 E. coli 2
NDM NDM-1 K. pneumoniae 1
KPC KPC-18 E. coli 1
VIM VIM-2 E. coli 1
IMP IMP-1 K. pneumoniae 1