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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Drug Dev Res. 2016 Nov 18;78(1):49–62. doi: 10.1002/ddr.21370

Figure 3.

Figure 3

Synthesis of the final compounds 9a-h and 10. Reagents and conditions: i) N-(4-bromophenyl)-2-chloroacetamide, K2CO3,anhydrou CH3CN, reflux, 5-7h;ii) 10% Pd/C, anhydrous EtOH, H2, Parr, 30 PSI, 2 h.