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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Adv Drug Deliv Rev. 2016 Aug 9;113:157–176. doi: 10.1016/j.addr.2016.08.001

Figure 8.

Figure 8

(a) Schematic illustration of chelator-free synthesis of *As (Or 69Ge)-SPION. (b) TEM image of oleic acid capped SPIONs (SPIONOA); inset shows the ferrofluidic behavior of SPIONOA. (c) TEM image of poly(acrylic acid)-modified SPIONs (SPIONPAA);inset depicts transfer of the SPIONs from oil phase to water phase. (d) In vivo lymph node PET imaging 2.5 h after subcutaneous injection of *As-SPIONPEG. (e) In vivo MR lymph node mapping 15 h post injection of SPIONPAA into the left footpad of the mouse. Adapted with permission from [24]. Copyright by John Wiley and Sons.