Table 2.
The biological and clinical parameters of controls and patients with NSCLC.
| Variables | NSCLC patients | Disease controls | Healthy controls | P value |
|---|---|---|---|---|
| Number of subjects | 188 | 112 | 130 | |
| Age (years) | 45.2 ± 12.3 | 47.1 ± 11.4 | 47.9 ± 13.2 | >0.05 |
| Sex (M/F) | 118/70 | 61/51 | 72/58 | >0.05 |
| BMI (kg/m2) | 25.3 ± 2.7 | 26.1 ± 3.0 | 25.5 ± 2.7 | >0.05 |
| Smoking subjects (M/F) | 94/17 | 45/15 | 60/17 | >0.05 |
| SBP (mmHg) | 130 ± 15 | 132 ± 14 | 133 ± 12 | >0.05 |
| DBP (mmHg) | 82 ± 10 | 80 ± 11 | 79 ± 12 | >0.05 |
| Glu (mmol/L) | 5.12 ± 1.55 | 5.30 ± 1.69 | 5.25 ± 1.77 | >0.05 |
| WBC (109/L) | 6.17 ± 2.22 | 5.74 ± 3.01 | 5.42 ± 2.15 | >0.05 |
| PLT (109/L) | 190.1 ± 21.5 | 199.3 ± 18.0 | 210.1 ± 20.1 | >0.05 |
| CRP (mg/L) | 5.5 (0.5–19.5)△ | 4.5 (0.5–14.6)△ | 2.4 (0.5–7.6) | <0.05 |
| PT (seconds) | 11.0 ± 3.1 | 11.6 ± 2.6 | 11.7 ± 2.2 | >0.05 |
| aPTT (seconds) | 24.1 ± 5.0 | 25.8 ± 3.9 | 26.0 ± 3.8 | >0.05 |
| Fbg (g/L) | 3.35 ± 1.20∗ | 2.68 ± 1.30 | 2.54 ± 2.01 | <0.01 |
| D-D (mg/L) | 0.65 ± 0.14∗ | 0.42 ± 0.10 | 0.26 ± 0.04 | <0.01 |
| FVIII:C (%) | 107.5 ± 12.3∗ | 95.1 ± 11.2 | 91.2 ± 13.0 | <0.05 |
| AT (%) | 77.0 ± 10.1∗ | 92.4 ± 10.8 | 98.5 ± 13.1 | <0.01 |
| TFPI-1 (ng/ml) | 51.0 ± 8.6∗ | 79.2 ± 13.2 | 87.1 ± 15.9 | <0.01 |
Data are presented as mean ± SD, and CRP is expressed with median and range. NSCLC: non-small cell lung cancer. BMI: body mass index. SBP: systolic blood pressure. DBP: diastolic blood pressure. GLU: serum glucose. WBC: white blood cell count. PLT: platelet count. CRP: C- reactive protein. PT: prothrombin time. aPTT: activated partial thromboplastin time. Fbg: fibrinogen. D-D: d-dimer. FVIII:C: coagulating factor VIII procoagulant activity. AT: antithrombin. TFPI-1: tissue factor pathway inhibitor-1. P value: compared among three groups. ∗P < 0.01: compared with disease controls and healthy controls. P < 0.05: compared with healthy controls.