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. 2017 Feb 9;7:42265. doi: 10.1038/srep42265

Figure 5. Cav1 rescues ER stress-induced endothelial dysfunction.

Figure 5

Immunofluorescence for Cav1 with quantification on right (A,D), and ER stress marker (BiP) with quantification on right (B,E), and endothelium-dependent vasorelaxation (C,F) in thoracic aortas (A,B,C) and MRA (D,E,F), of C57Bl/6 mice treated with tunicamycin (Tun) or vehicle control (Veh). and infected ex vivo with AD Cav1 or AD LacZ. *p < 0.05 between Tun + AD LacZ vs. Veh + AD LacZ, Veh + AD Cav1 and Tun + AD Cav1. #p < 0.05 between Veh + AD Cav1 vs. Veh + AD LacZ and Tun + AD Cav1. ^p < 0.05 between Tun + AD Cav1 vs. Veh + AD Cav1 and Veh + AD LacZ. Yellow arrows point to BiP expression in the endothelium.