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| Groups | Necrosis | Edema | Inflammation |
|---|---|---|---|
| Diabetic control | − | − | + |
| Dia + IR | +++ | +++ | +++ |
| Dia + MNG 40 + IR | + | − | ++ |
The changes are ranked as: (−): no change; (+): focal change; (++): patchy change; (+++): confluent change. Dia + IR: diabetes + ischemia-reperfusion; Dia + MNG 40 + IR: diabetes + mangiferin 40 mg/kg + ischemia-reperfusion; n = 3 per group.
