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. 2017 Feb 9;7:42436. doi: 10.1038/srep42436

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) A heat map depicting the relative abundance of 12,380 proteins identified across 44 samples (22 CRC and 22 AT). The color key indicates the relative abundance of each protein (0 to 1.0) across 44 samples. (B) A summary of statistical analyses of differentially expressed proteins (right, each color representing a category; ratio of CRC/AT was calculated based on the average of 22 samples). (C) Volcano plot demonstrating the fold change of protein abundance between CRC and AT. The x-axis represents the log2 of fold changes (CRC versus AT), and the y-axis represents the statistically significant p-value (−log10 of p-value, n = 22).