Table 1. Spearman correlation analysis of pain levels verses peak scores or cumulative scores at 30–39 and 40–49 days post-induction in wild-type, Asic1a ^−/−, Asic2 ^−/− and Asic3 ^−/− EAE mice.

	D30-39				D40-49
	Wildtype	Asic1a−/−	Asic2−/−	Asic3−/−	Wildtype	Asic1a−/−	Asic2−/−	Asic3−/−
	Max. score
Spearman r	−0.08778	−0.02700	0.2722	0.1248	0.1077	−0.3021	0.08944	−0.06561
95% CI	−0.3826 to 0.2233	−0.6294 to 0.5957	−0.3743 to 0.7406	−0.2870 to 0.4977	−0.1970 to 0.3934	−0.7720 to 0.3813	−0.5248 to 0.6424	−0.4313 to 0.3186
p value	0.5710	0.6190	0.6636	0.5436	0.4764	0.1498	0.3727	0.7353
Significance	ns	ns	ns	ns	ns	ns	ns	ns
	Cumulative score
Spearman r	0.1566	0.1541	0.1539	0.003135	0.1892	−0.1125	−0.1986	−0.2094
95% CI	−0.1559 to 0.4407	−0.5066 to 0.7008	−0.4758 to 0.6793	−0.3949 to 0.4002	−0.1157 to 0.4615	−0.6785 to 0.5374	−0.7033 to 0.4393	−0.5430 to 0.1811
p value	0.3099	0.6529	0.6494	0.9879	0.2080	0.6680	0.4043	0.2755
Significance	ns	ns	ns	ns	ns	ns	ns	ns