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. 2016 Dec 12;22(2):139–147. doi: 10.1111/tmi.12814

Table 4.

Univariate and multivariate regression analysis of RR measurement over time by different observers, N = 859

Variable Univariate Multivariate
Coefficient, 95% CI SE P‐Value Coefficient, 95% CI SE P‐Value
Level 1
Female 0.39 (−2.28 to 3.08) 1.37 0.771
Age (months) −0.26 (−0.39 to −0.12) 0.07 <0.001 −0.31 (−0.39 to −0.14) 0.04 <0.001
Temperature at baseline (°C) 5.77 (2.75 to 8.79) 1.54 <0.001 5.82 (3.07 to 8.72) 1.43 <0.001
History of rapid breathing 2.70 (−0.01 to 5.37) 1.37 0.048 2.83 (0.31 to 5.17) 1.23 0.022
Duration of illness −1.18 (−3.51 to 3.15) 1.69 0.915
Level 2
Effect of time (minutes)
10 Baseline Baseline
20 −0.56 (−1.71 to 0.58) 0.58 0.338 −0.04 (−1.15– 1.07) 0.57 0.936
30 −0.46 (−1.60 to 0.68) 0.58 0.432 0.19 (−0.92 to 1.31) 0.57 0.942
40 −0.77 (−1.93 to 0.39) 0.59 0.196 −0.41 (−1.53 to 0.71) 0.57 0.475
50 −0.90 (−2.09 to 0.28) 0.60 0.134 −0.01 (−1.17 to 1.16) 0.59 0.991
60 −1.25 (−2.45 to −0.05) 0.61 0.041 −0.62 (−1.79 to 0.55) 0.59 0.300
Child's state
Awake/calm Baseline Baseline
Sleeping −3.83 (−4.95 to −2.69) 0.59 <0.001 −3.94 (−5.09 to −2.79) 0.59 <0.001
Agitated −1.85 (−2.88 to −0.82) 0.53 <0.001 −1.97 (−3.02 to −0.93) 0.53 <0.001
Feeding 2.0 (0.25–3.76) 0.90 0.025 1.93 (0.16–3.69) 0.90 0.030
Level 3
Readers
Research Nurse Baseline Baseline
Observer 1 0.53 (0.19–0.86) 0.17 0.002 0.52 (0.19–0.85) 0.17 0.002
Observer 2 0.78 (0.44–1.11) 0.17 <0.001 0.78 (0.44–1.12) 0.17 <0.001

The multivariate analysis was performed using the variables with P values <0.05 from the univariate analysis. Final model included age (as continuous variable), temperature at baseline, history of rapid breathing, the child's state at the time of measuring the respiratory rate and readers. Intraclass variation = 87%. Bold P‐values indicates significant associations