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. 2017 Feb 9;7:42079. doi: 10.1038/srep42079

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Vestibular function of Gfi1^+/+ (+/+), Gfi1^Cre/+ (cre/+) and Gfi1^Cre/Cre (cre/cre) littermates was measured by vestibular sensory-evoked potentials (VsEP) at 3, 5 and 10 months of age. Two of the four Gfi1^Cre/Cre animals (number shown in parentheses) had absent responses at 3 months. Average threshold shown for Gfi1^Cre/Cre reflects only those animals with measurable responses (n = 2). Analysis of variance showed no significant differences in VsEP thresholds between Gfi1^+/+ and Gfi1^Cre/+ at all ages tested (Gfi1^+/+ n = 2, 4, and 3 mice at 3, 5 and 10 months respectively, Gfi1^Cre/+ n = 4, 10, and 8 mice at 3, 5 and 10 months respectively).