Table 1. Peak Na⁺ current density and persistent Na⁺ current.

Na+ current tested	Con				CaM
	Peak current density	Persistent Na+ current	n		Peak current density	Persistent Na+ current	n
	pApF	% of peak			pApF	% of peak
NaV1.5TTX-S	−210 ± 13	0.63 ± 0.08	35		−211 ± 16	0.54 ± 0.09	25
D1790G	−170 ± 22	0.76 ± 0.11	22		−180 ± 22	0.57 ± 0.09	17
Y1795C	−205 ± 21	1.74 ± 0.19a	18		−192 ± 12	0.48 ± 0.07	18
E1901Q	−175 ± 18	2.47 ± 0.53a	13		−176 ± 24	0.30 ± 0.07	13
Q1909R	−188 ± 21	1.40 ± 0.12a	15		−200 ± 28	0.50 ± 0.07	15
R1913H	−184 ± 16	1.51 ± 0.21a	15		−188 ± 20	0.50 ± 0.08	15
L1917K	−185 ± 21	0.27 ± 0.06	11		−175 ± 25	0.29 ± 0.06	11
ΔKPQ	−171 ± 19	1.90 ± 0.19a	14		−170 ± 27	1.95 ± 0.21a	14
NaV1.2 WT	−228 ± 37	0.66 ± 0.17	16		−193 ± 16	0.50 ± 0.13	16
H1853R	−204 ± 17	1.41 ± 0.20b	15		−181 ± 27	0.61 ± 0.13b	15
R1918H	−158 ± 27	3.17 ± 0.53b	20		−162 ± 27	0.80 ± 0.12b	20
NaV1.6 WT	−70 ± 4.7	13.20 ± 2.34	24		−79 ± 13	5.01 ± 0.92c	24
NaV1.6TTX-R in Purkinje neurons	−119 ± 16	6.96 ± 0.91	12		−130 ± 10	3.36 ± 0.45c	10
Purkinje neurons	−137 ± 13	9.03 ± 0.74	22		−132 ± 11	3.75 ± 0.54c	18

^aP < 0.01 compared with Na_V1.5^TTX-S.

^bP < 0.01 compared with Na_V1.2.

^cP < 0.01 compared with Con.