Table 3.
Relationship between Growth Differentiation Factor 15(GDF-15) and risk of 28-day mortality
| GDF-15 on admission vs 28 days follow-up death (Model 1 and 2) | ||||||
|---|---|---|---|---|---|---|
| Continuous GDF-15 analysis (per SD increment) | P-value | Tertile 1 | Tertile 2 | Tertile 3 | P for trend | |
| N/N eventsb | 46/13 | 15/1 | 16/3 | 15/9 | ||
| HR (95% CI) (age and gender adjusted) | 2.76 (1.37–5.56) | 0.004 | 1.0 (ref) | 1.21 (0.19–7.77) | 3.48 (0.54–22.34) | 0.124 |
| HR (95% CI) (age, gender and CRP adjusted)a | 3.48 (1.78–6.80) | <0.001 | 1.0 (ref) | 1.14 (0.16–8.21) | 2.65 (0.36–19.41) | 0.036 |
SD standard deviation, HR hazard ratio, CI confidence interval, CRP C-reactive protein
aBackward elimination model
bdeath within 28 days from admission