Table 4.
Demographic, serological, and virological characteristics according to the clinical classifications of the 90 HBsAg-positive subjects with a conclusive clinical diagnosis
| HBsAg pos. non-viremic asymptomatic carriers | HBsAg pos. viremic asymptomatic carriers | HBsAg pos. patients with chronic hepatitis | HBsAg-pos. patients with cirrhosis | |
|---|---|---|---|---|
| N° of patients | 29 | 43 | 14 | 4 |
| Age, years, median (range) | 32 (22–58) | 32.5 (20–55) | 32.5 (18–44) | 32.5 (25–35) |
| Males, n° (%) | 25 (86) | 35 (83.3) | 14 | 4 |
| Status in country, n° (% by row) | ||||
| Undocumented immigrants, 63 cases | 14 (22.2) | 32 (50.8) | 13 (20.6) | 4 (6.4) |
| Low-income refugees, 27 cases | 15 (52) | 11 (26.2) | 1 (7) | 0 |
| In Italy for month, mean ± SD | 35.7 ± 32.7 | 42 ± 58.6 | 49.4 ± 28.8 | 50 ± 52.3 |
| Years of schooling, mean ± SD | 3.5 ± 4.2 | 2.5 ± 4 | 11.9 ± 19.8 | 2.7 ± 3.8 |
| Country of origin, n° (% by row) | ||||
| Eastern Europe, 10 cases | 1 (10.0) | 5 (50.0) | 4 (40.0) | 0 |
| North Africa, 1 case | 0 | 1 (100) | 0 | 0 |
| SSA, 75 cases | 27 (36) | 35 (46.7) | 10 (13.3) | 3 (4) |
| Asia, 4 cases | 1 (25) | 2 (50) | 0 | 1 (25) |
| America, no cases | 0 | 0 | 0 | 0 |
| Anti-delta-positive, n°(% by column) | 0 | 1 (2.4) | 1 (7) | 0 |
| HBeAg positive/anti-HBe negative, n° (% by column) | 0 | 0 | 4 (28.6) | 2 (50) |
| HBeAg negative/anti-HBe positive, n° (% by column) | 29 (100) | 43 (100) | 10 (71.4) | 2 (50) |
| HBV DNA, IU/ml, median (range) | -- | 620 (12–73 000) | 8,500 (2.4E3–1.0E9) |
1.2E7 (1.3E–1.7E8) |
| AST, IU/ml, mean ± SD | 18 ± 3.7 | 23.6 ± 7.2 | 72.7 ± 82.5 | 41 ± 22 |
| ALT, IU/ml, mean ± SD | 19 ± 4.3 | 24.7 ± 7 | 98.5 ± 117.8 | 53 ± 32.2 |
| HBV genotype, n° (% by row) | ||||
| A | // | 8 (72.7) | 2 (18.2) | 1 (9.1) |
| C | 0 | 0 | 1 (25) | |
| D | 4 (57.1) | 3 (42.9) | 0 | |
| E | 18 (64.3) | 8 (28.6) | 2 (7.1) | |
| Not determined | 13 (92.9) | 1 (7.1) | 0 | |
AST aspartate-aminotransferases, ALT alanine-aminotransferase