Table 1.
Histomorphometry of the femur two-way analysis of variance
| Lean STD | Lean + GEN | Obese STD | Obese + GEN | Genotype effect (P) | Treatment effect (P) | Genotype * treatment interaction (P) | |
|---|---|---|---|---|---|---|---|
| Starting body mass (g) | 22.1 ± 0.92 | 21.7 ± 0.53 | 37.0 ± 1.86 | 36.54 ± 1.11 | 0.01 | 0.73 | 0.99 |
| Final body mass (g) | 24.8 ± 0.92 | 23.4 ± 0.46 | 50.7 ± 2.28 | 43.7 ± 1.29 | 0.01 | 0.01 | 0.06 |
| PE Bone area (B.Ar.; mm2) | 0.79 ± 0.15 | 0.50 ± 0.07 | 0.85 ± 0.06 | 0.84 ± 0.04 | 0.04 | 0.11 | 0.12 |
| PE Total area (Tt.Ar.; mm2) | 1.46 ± 0.26 | 0.84 ± 0.13 | 1.64 ± 0.17 | 1.44 ± 0.09 | 0.04 | 0.03 | 0.25 |
| MS Cortical area (Ct.Ar.; mm2) | 1.15 ± 0.06 | 1.20 ± 0.06 | 1.17 ± 0.03 | 1.08 ± 0.07 | 0.36 | 0.70 | 0.22 |
| MS IMAX (mm4) | 2.17 ± 0.20 | 2.11 ± 0.25 | 2.06 ± 0.12 | 1.98 ± 0.27 | 0.59 | 0.75 | 0.95 |
| MS IMIN (mm4) | 1.07 ± 0.12 | 1.29 ± 0.07 | 1.25 ± 0.06 | 1.09 ± 0.13 | 0.91 | 0.77 | 0. 09 |
| MS J (mm4) | 3.24 ± 0.31 | 3.40 ± 0.31 | 3.31 ± 0.17 | 3.07 ± 0.40 | 0.67 | 0.90 | 0.53 |
Data displayed as mean ± SE
STD fed standard chow; GEN fed 600 genistein/kg
PE proximal epiphysis of the femur; MS midshaft of the femur
IMAX maximum second moment of area; IMIN minimum second moment of area; J polar moment of area