Table 3.

Key results of Recruitment Maneuvers in in silico ARDS patients with varying severity and cardiac output

	Moderate ARDS, High CO [25]		Moderate ARDS, Normal CO [26]		Severe ARDS, High CO [27]
RM	MRS	SI	MRS	SI	MRS	SI
End RM PEEP, cm H2O	10	10	10	10	15	10
RecruitmentB (baseline), %	78	78	8	87	57	57
RecruitmentM (maximum), %	97	80	100	97	98	65.
R Ratio	19.59	2.50	13.00	10.31	41.84	12.31
∆ CO (at max PAW), l min−1	−2.3	−1.7	−1.6	−1.2	−2.3	−1.5
∆ RVEDV (at max PAW), ml	−14	−6	−55	−29	−18	−10
DO2 (baseline), ml min−1	1086	1086	754	754	902	902
∆ DO2 (at max PAW), ml min−1	810	834	453	540	697	689
∆ DO2 (post RM), ml min−1	1144	1097	790	786	1012	971
RAP (baseline), mm Hg	9	9	11	11	11	11
RAP (at max PAW), mm Hg	18	12	21	15	23	16
PF ratio (baseline), mm Hg	199	199	196	196	65	65
PF ratio (post RM), mm Hg	363	213	337	309	347	86

List of Abbreviations: RM recruitment maneuver, PEEP positive end expiratory pressure, R Ratio recruitment ratio ((recruitment_M -recruitment_B)/recruitment_B × 100), ∆ CO change in cardiac output relative to baseline, ∆ RVEDV change in right ventricle end diastolic volume relative to baseline, DO ₂ oxygen delivery, ∆ DO ₂ change in oxygen deliver relative to baseline, PF ratio ratio of arterial partial pressure of oxygen to fraction of oxygen in inhaled air, max P _AW maximum airway pressure, RAP right atrial pressures