Table 4.

Key results of Maximum Recruitment Strategy (MRS) in 20 in silico ARDS patients

	All Patients		Severe ARDS		Moderate ARDS		Mild ARDS
	mean	sd	mean	sd	mean	sd	mean	sd
PEEP (baseline), cmH2O	10.0	0	10.0	0	10.0	0	10.0	0
PEEP (post RM), cmH2O	24.5	2	25.0	0	25.0	0	21.7	6
Recruitment (baseline), %	63.3	18	49.7	11	75.7	4	88.0	11
Recruitment (at max PAW), %	93.7	3	92.4	2	94.2	3	97.7	3
CO (baseline), l min−1	11.6	0.2	11.7	0.1	11.6	0.2	11.3	0.3
CO (at max PAW), l min−1	8.3	0.3	8.4	0.2	8.2	0.2	8.1	0.3
CO (post RM), l min-1	10.3	0.2	10.3	0.1	10.2	0.1	10.4	0.1
∆ RVEDV (at max PAW), ml	−48	6.1	−49	6.2	−46	5.9	−52	4.6
∆ RVESV (at max PAW), ml	−33	21	−33	23	−43	16.2	−15	18
DO2 (baseline), ml min−1	1556	340	1316	244	1809	138	1929	194
DO2 (at max PAW), ml min−1	1398	81	1406	94	1385	74	1403	63
DO2 (post RM), ml min−1	1642	114	1595	99	1671	97	1759	124
PRA (baseline), mmHg	6.5	4	6.7	4	5.5	4	7.8	6
PRA (at max PAW), mmHg	7.8	4	8.8	4	7.3	4	4.9	0
PRA (post RM), mmHg	7.6	4	7.4	4	6.4	4	10.7	0
PF ratio (baseline), mmHg	102	85	54	10	115	50	250	125
PF ratio (at max PAW), mmHg	206	72	182	53	207	81	298	48
PF ratio (post RM), mmHg	140	78	92	23	179	82	243	78
Dynamic strain (baseline),	0.18	0.03	0.18	0.04	0.19	0.03	0.18	0.02
Dynamic strain (at max PAW)	0.10	0.02	0.12	0..02	0.10	0.02	0.09	0.01

List of Abbreviations: RM recruitment maneuver, PEEP positive end expiratory pressure, CO cardiac output, ∆ RVEDV change in right ventricle end diastolic volume relative to baseline, ∆ LVEDV change in left ventricle end diastolic volume relative to baseline, ∆ RVESV change in right ventricle end systolic volume relative to baseline, ∆ LVEDV change in left ventricle end systolic volume relative to baseline, P _RA right atrial pressure, DO ₂ oxygen delivery, PF ratio ratio of arterial partial pressure of oxygen to fraction of oxygen in inhaled air, max P _AW maximum airway pressure