Fig. 4. Bile acids are sufficient to suppress fatty acid oxidation genes in primary cardiomyocytes.
Neonatal cardiomyocytes, incubated with CDCA (100µM) for 4 hours, were evaluated for key genes regulating fatty acid and glucose oxidation. 18S was used as the loading control. Values are depicted as fold change to Vehicle values (n=3 sets; *p < 0.05; **p<0.001 compared to vehicle treated cardiomyocytes).