Figure 3.

a) Schematic illustration of (i) riluzole loaded in iron oxide NC and (ii) blocking sodium ion channels by this NC, which prevents glutamate receptor activation and glutamate secretion, therefore reducing cancer cell growth. Reprinted with permission from ref. ⁹² Copyright 2016 American Chemical Society, b) Schematic illustration of cancer treatment in mice with RBC-coated Au NCs (RBC-AuNCs). Reprinted with permission from ref. ¹⁰⁰ Copyright 2014 the American Chemical Society, c) Schematic of receptor-mediated cellular uptake of a biotin-functionalized truncated octahedral DNA NC by LOX-1 overexpressing cells (e.g. fibroblast cells) Reprinted with permission from ref. ¹⁰¹ Copyright 2016 the American Chemical Society.