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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2015 Dec 30;171(7):958–970. doi: 10.1002/ajmg.b.32412

Table II.

Twin Correlations and Variances and Univariate Twin Modeling Parameters

Variable N (pairs) Twin Correlations Twin Variances Cross-Twin, Cross-Trait
(Alcohol Problems)

MZ DZ rMZ rDZ MZ DZ rMZ rDZ
CATSS-9/12
ADHD
  Hyperactive/
Impulsive
3,421 4,253 .70 [.66, .73] .13 [.09, .16] 1.77 [1.61, 1.94] 2.36 [2.20, 2.52] .11 [.04, .18] .05 [−.02, .12]
  Inattentive 3,421 4,253 .61 [.58, .65] .11 [.07, .14] 2.50 [2.30, 2.70] 3.15 [2.97, 3.33] .04 [−.03, .10] .05 [−.02, .12]
Disruptive behaviors 3,420 4,251 .64 [.59, .68] .30 [.26, .34] 0.89 [0.79, 1.00] 1.17 [1.06, 1.28] .08 [.01, .16] .08 [.003, .15]
CATSS-18
Alcohol problemsa 726 748 .69 [.62, .76] .33 [.21, .46] 18.92 [15.88, 21.96] 18.69 [15.98, 21.39] -- --
Univariate Twin Modeling Parameter Estimates from Best-Fitting Models
Model Additive (a2) Dominant (d2) Non-shared Environmental
(e2)
Sibling Contrast (s)
CATSS-9/12
ADHD
  Hyperactive/
Impulsive
AEs .82 [.79, .85] -- .19 [.15, .22] −.16 [−.19, −.14]
  Inattentive AEs .76 [.72, .79] -- .24 [.21, .28] −.15 [−.18, −.13]
Disruptive behaviors AEs .68 [.62, .75] -- .32 [.25, .38] −.04 [−.08, −.003]
CATSS-18
Alcohol problems AE .69 [.63, .75] -- .31 [.25, .38] --

Note. CATSS-9/12 reports are provided by caregivers, and CATSS-18 reports are provided by twins. Values are estimate [95% CI]. All parameter estimates control for pair sex. Twin correlations were estimated from models constraining intercepts and variances to equality across twins and zygosity groups. Variances were estimated from similar models without constraints for equal variances across zygosity groups. Unless otherwise noted, all MZ and DZ variances differed significantly from each other, Wald p < .05. Proportions of additive and non-shared environmental variance were calculated independent of the sibling contrast effects (i.e., a2 + e2 = 1).

a

Twin variances did not significantly differ from each other, Wald p = .91.