Table 3. Haplotype analysis of SLC6A3 (DAT) gene in patients with alcohol dependence (N = 637) and controls (N = 523).
Haplotype block 1: | Frequency | p | |||||
rs37020 | rs464049 | rs460700 | rs460000 | rs403636 | AD | Control | |
C | G | C | T | C | 0.487 | 0.512 | 0.236 |
A | A | T | G | A | 0.318 | 0.311 | 0.711 |
C | G | T | G | C | 0.117 | 0.100 | 0.209 |
A | A | T | G | C | 0.029 | 0.026 | 0.648 |
C | G | C | T | C | 0.014 | 0.007 | 0.085 |
Haplotype block 2: | Frequency | p | |||||
rs2975226 | rs2652511 | rs2550948 | AD | Control | |||
T | T | G | 0.829 | 0.851 | 0.159 | ||
A | C | A | 0.153 | 0.187 | 0.094 | ||
A | C | G | 0.013 | 0.013 | 0.855 |