Skip to main content
. 2017 Feb 9;12(2):e0171748. doi: 10.1371/journal.pone.0171748

Fig 3. The midbrain dopamine system of the Cd24 mutant mouse is normal.

Fig 3

(A) Stereological estimations of the number of SNpc TH+ cells at 8 weeks of age. (B) Distance travelled in the open field arena by 2-year-old Cd24-/- and Cd24+/+ mice. (C) Stereological estimations of the number of SNpc TH+ cells at 2 years of age. (D) Tyrosine hydroxylase (TH) immunohistochemistry on coronal sections of a brain of a 2-year-old Cd24-/- mouse (left column) and a Cd24+/+ littermate (right column), at the level of the striatum. (E) A coronal section of the SNpc at the level of the fasciculus retroflexus (FR) and the caudal end of the mammillary bodies (MM). (F) Images of the VTA and SNpc at the level of the medial terminal nucleus of the accessory optic tract (mtn). Co-ordinates in the right-hand corners of panels D, E and F indicate location of the coronal plane relative to bregma. The scale bar in panel F represents 1cm in panel D, 200μm in panel E, and 300μm in panel F.