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. 2017 Feb;58(2):933–943. doi: 10.1167/iovs.16-19782

Figure 1.

Figure 1

Adenosine deaminase-2 activity in human macrophages. (A) Adenosine deaminase-2 activity in human macrophages treated with AGA, albumin, or control. There is marked increase in ADA2 activity in human macrophages after treatment with AGA compared with albumin or control (*P < 0.05 versus control group, #P < 0.05 versus albumin group; n = 3–4). (B) Adenosine deaminase-2 activity in AGA-treated human macrophages after transfection with miR-146b-3p mimic or control miR (nontargeting miRNA). Human macrophages were transfected with miR-146b-3p or control miR and then treated with AGA, and ADA2 activity was measured in the medium. Adenosine deaminase-2 activity was significantly reduced after transfection with miR-146b-3p compared with control miR (*P < 0.05 versus control miR group; n = 3).