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. 2017 Feb;58(2):933–943. doi: 10.1167/iovs.16-19782

Figure 9.

Figure 9

Effect of human macrophages CM on expression of adhesion molecule ICAM-1 in hRECs. (A) Western blot of ICAM-1 in hRECs treated with the CM of AGA-, albumin-, or control-treated macrophages or direct AGA or albumin. There is significant up-regulation of ICAM-1 expression in hRECs treated with CM of AGA-treated macrophages compared with the CM of control macrophages or albumin-treated macrophages (*P < 0.05 versus control CM group, #P < 0.05 versus albumin CM group). Direct treatment of hRECs with AGA did not show any significant increases in ICAM-1 expression compared with albumin treatment (P > 0.05; n = 4). (B) Western blot of ICAM-1 in hRECs treated with the CM of miR-146b-3p–transfected AGA-treated macrophages showing significant decrease in ICAM-1 expression in hRECs after treatment with the CM of miR-146b-3p–transfected AGA-treated macrophages compared with the CM of control miR-transfected AGA-treated macrophages (*P < 0.05 versus control miR CM group; n = 4).