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. 2017 Feb 9;10(2):211–220. doi: 10.1016/j.tranon.2017.01.010

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

MMP7 restoration reverses the effects of miR-489. (A) miR-489 overexpressing HCCLM3 cells that were infected with empty vector (EV) or MMP7 retroviruses were confirmed by western blotting for MMP7 expression. n = 3 repeats with similar results, *P < .05 by t test. (B) MMP7 restoration significantly promoted the migration of miR-489 overexpressing HCCLM3 cells. (C) MMP7 restoration evidently facilitated cell migration and invasion in miR-489 overexpressing HCCLM3 cells. n = 3 repeats with similar results, *P < .05 by t test.