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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Ann Rheum Dis. 2015 Sep 11;75(8):1558–1566. doi: 10.1136/annrheumdis-2015-208119

Table 4.

Evidence of expression quantitative trait loci (eQTL)

Subgroup Mapped Genes Immunochip lead SNP eQTL within r2 >0.9 References
IIM UBE2L3 | YDJC rs11089637 UBE2L3, RIMBP3 [32] [33]
PM UBE3B | MMAB rs7956536 KCTD10, MMAB [32] [33] [34]
PM RGS1 rs7535818 RGS1 [32]
PM NAB1 rs2286896 STAT1 [35]
DM+JDM GSDMB rs1008723 ORMDL3, MED24, KRT222, NR1D1, GSDMB [34] [35] [36] [33]

eQTLs for the expression of a gene in cells with an immune function (Lymphoblastoid and Monocytes). RegulomeDB,[37] Genevar,[38] and the Pritchard lab eQTL browser (http://eqtl.uchicago.edu/cgi-bin/gbrowse/eqtl/) were interrogated. The most significant SNP or any SNP with r2 ≥0.9 with most significant SNP was used. Genes are indicated along with studies in which the eQTLs were reported.