Fig 3.

IFN-γ (A), IL-10 (B) and IL-17 (C) production in 72h spleen cell culture supernatant of mice infected for 20 weeks with human and porcine MST22 (red) and human or porcine MST91 (green) Mah isolates. Cells were unstimulated (filled bars) or stimulated with culture filtrate (striped bars). Results represent mean cytokine levels (pg/mL) ± SEM of 5 mice tested individually in each group. Statistical significance is depicted for MST22 strains as compared to MST91 strains (*: p<0.05; **: p<0.005; n.s.: non-significant).