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. Author manuscript; available in PMC: 2017 Feb 9.
Published in final edited form as: Cell Signal. 2010 Jun 4;22(10):1502–1512. doi: 10.1016/j.cellsig.2010.05.019

Table 1.

Kinetic parameters describing p38 MAPK isoform-mediated phosphorylation of MK2, MK3, and MK5.

p38α p38β p38δ p38γ
Km (nM)
 MK2 15.2 12.7 23.7 22.7
 MK3.1 6.01 5.54 13.9 3.40
 MK3.2 19.0 25.6 nd nd
 MK5 17.5 14.8 15.8 8.91
Vmax (pmol/min)
 MK2 0.546 0.618 0.138 0.0185
 MK3.1 0.537 0.883 0.208 0.0214
 MK3.2 0.0296 0.0177 nd nd
 MK5 2.59 4.62 0.503 0.0402
Vmax/Km
 MK2 36 49 5.8 0.82
 MK3.1 89 160 8.4 2.4
 MK3.2 1.6 0.69 nd nd
 MK5 150 310 32 4.5