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. 2016 Dec 28;112(3):460–472. doi: 10.1016/j.bpj.2016.10.041

Table 2.

Protected DNA Length (bp) in the PANS, from Atomistic MD Simulations and Experiment

MD Simulations
AFM Dataa
MNase Protection
Median Range Median Rangeb Peaksa,c
Disome 43 14 36 8 15–45
Tetrasome 69 10 74 16 46–75
Hexasome 110 7 109 18 76–120
Octasome 147 0d 148 6 140–150
a

Obtained from analysis of the experimental data representing a mix of PANS.

b

Interquartile range.

c

Data from Teves and Henikoff (31) (see section Interpretation of genome-wide mapping data).

d

Modeled octasome structure does not contain linker DNA.