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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Sep 6;9(2):10.1002/wnan.1424. doi: 10.1002/wnan.1424

Figure 13.

Figure 13

Schematic of different decoration strategies for self-assembling peptide fibers (SAFs). a) Peptide fibers are assembled by mixing equal amounts of SAF-p1 and SAF-p2a at pH 7.4. b) Non-covalent decoration using short peptides (SAF-tags). Rhodamine was attached to the N-terminus of the tag and visualized via light microscopy. c) “Click” chemistry was employed for post-assembly functionalization of fibers incorporating azide groups. The decoration was carried out by reacting the surface azide moieties with biotin-alkyne, followed by the addition of 5 nm streptavidin nanogold. The decorated nanofiber was confirmed with TEM imaging. Reproduced from Ref 76 with permission, Copyright 2010, The Royal Society of Chemistry.