Table 6.
NMR data for argimycins PIV-PVI (1H, 500 MHz; 13C, 150 MHz, in CD3OD).
| Argimycin PIV |
Argimycin PV |
Argimycin PVI |
||||
|---|---|---|---|---|---|---|
| Carbon | δH (mult, J, Hz) | δC (ppm) | δH (mult, J, Hz) | δC (ppm) | δH (mult, J, Hz) | δC (ppm) |
| 2 | 3.27 (app quintet, ca. 6.3)3.02 (app quintet, ca. 6.3) | 35.5 | 3.18 (app quintet, ca. 6.3)3.07 (app quintet, ca. 6.3) | 39.1 | 3.13 (m)3.00 (m) | 40.3 |
| 3 | 1.97 (m) 1.72 (m) | 23.3 | 1.95 (m) 1.68 (m) | 16.4 | 1.78 (m) 1.69 (m) | 17.6 |
| 4 | 3.89 (dd, 6.6, 3.0) | 68.9 | 1.89 (m) | 30.9 | 1.99 (m) | 21.3 |
| 4a | – | 77.4 | – | 76.3 | 3.02 (m) | 39.1 |
| 5 | – | 142.4 | – | 144.8 | – | 140.5 |
| 6 | 7.06 (br d, 6.0) | 135.5 | 7.02 (br d, 6.0) | 134.5 | 7.17 (br d, 5.8) | 137.2 |
| 7 | 6.02 (br d, 6.0) | 126.6 | 6.00 (br d, 6.0) | 126.7 | 6.15 (br dt, 5.9) | 129.3 |
| 7a | 4.36 (br s) | 67.0 | 4.13 (br s) | 66.9 | 4.25 (dd, 6.5, 2.3) | 59.4 |
| 8 | 6.15 (d, 11.2) | 125.2 | 6.10 (d, 11.2) | 123.0 | 6.04 (d, 11.1) | 123.4 |
| 9 | 6.49 (ddq, 14, 11.2, 1.5) | 127.5 | 6.47 (ddq, 14.0, 11.2, 1.6) | 127.4 | 6.52 (ddq, 14, 11.1, 1.6) | 127.6 |
| 10 | 5.91 (dq, 14, 6.7) | 132.1 | 5.88 (dq, 14.0, 6.8) | 131.5 | 5.83 (dq, 14, 6.8) | 130.2 |
| 11 | 1.85 (br d, 6.7) | 17.1 | 1.84 (dd, 6.9, 1) | 17.1 | 1.83 (brd, 6.9) | 16.9 |