Table 2.

The associations between systolic BP trajectories with carotid intima-media thickness and left ventricular mass index

Trajectories	Intima-media thickness			Left ventricular mass index
	N	β (95% CI)	P value	N	β (95% CI)	P value
	Model 1	N=551			N=546
Low-increasing	268	Reference		269	Reference
Moderate-increasing	215	0.018 (0.006–0.030)	0.003	212	6.824 (4.545–8.941)	<0.001
High-increasing	68	0.047 (0.029–0.064)	<0.001	65	14.313 (10.873–17.508)	<0.001
		P for trend =0.001			P for trend <0.001
Model 2	N=551			N=546
Low-increasing	268	Reference		269	Reference
Moderate-increasing	215	0.017 (0.005–0.030)	0.006	212	3.582 (1.428–5.840)	0.001
High-increasing	68	0.046 (0.028–0.065)	<0.001	65	9.119 (5.841–12.398)	<0.001
		P for trend <0.001			P for trend <0.001
Model 3*	N=545		N=539
Low-increasing	265	Reference		265	Reference
Moderate-increasing	212	0.013 (0.001–0.026)	0.039	209	3.225 (1.022–5.428)	0.004
High –increasing	68	0.039 (0.020–0.058)	<0.001	65	8.477 (5.110–11.843)	<0.001
		P for trend =0.010			P for trend <0.001
Model 4*	N=545			N=539
Low-increasing	265	Reference		265	Reference
Moderate-increasing	212	0.019 (0.005–0.032)	0.007	209	2.785 (0.448–5.121)	0.019
High –increasing	68	0.051 (0.027–0.074)	<0.001	65	7.451 (3.644–11.257)	<0.001
		P for trend <0.001			P for trend <0.001

BP = blood pressure; CI = confidence interval

Model 1= Unadjusted model; Model 2= age, race, sex; Model 3 = Model 2+ body mass index and father’s education level; Model 3= Model 4+ systolic BP and diastolic BP

^*Six participants were excluded due to missing values of father’s education in Model 3 and Model 4 for intima-media thickness, seven participants were excluded due to missing values of father’s education in Model 3 and Model 4 for left ventricular mass index