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. 2017 Feb 10;9:20. doi: 10.3389/fnagi.2017.00020

Table 7.

SNPs within loci associated with mitochondrial homeostasis recognized as PD susceptibility factors by GWASs.

Gene/locus SNP MAF (1000 genomes project) Risk allele: OR Study
SREBF1/RAI1 Ch 17 rs11868035 g.17715101G>A c.*835C>T (splice region variant) G = 0.4876 G: OR = 1.18 Do et al., 2011
MCCC1 Ch 3 rs12637471 g.182762437G>A c.732+764C>T (intron variant) A = 0.3375 G: OR = 1.1876 Nalls et al., 2014
rs11711441 g.182821275G>A (intron variant) A = 0.1406 G: OR = 1.19 Nalls et al., 2011
rs10513789 g.182760073T>G c.733-535A>C (intron variant) G = 0.3115 T: OR = 1.25 Do et al., 2011

Ch, Chromosome. Data compiled from the GWAS catalog database, the dbSNP and the e!Ensembl (Sherry et al., 2001; Welter et al., 2014; Yates et al., 2016).

*

Denotes SNPs in 3'-UTR.