Table 7.

SNPs within loci associated with mitochondrial homeostasis recognized as PD susceptibility factors by GWASs.

Gene/locus	SNP	MAF (1000 genomes project)	Risk allele: OR	Study
SREBF1/RAI1 Ch 17	rs11868035 g.17715101G>A c.*835C>T (splice region variant)	G = 0.4876	G: OR = 1.18	Do et al., 2011
MCCC1 Ch 3	rs12637471 g.182762437G>A c.732+764C>T (intron variant)	A = 0.3375	G: OR = 1.1876	Nalls et al., 2014
	rs11711441 g.182821275G>A (intron variant)	A = 0.1406	G: OR = 1.19	Nalls et al., 2011
	rs10513789 g.182760073T>G c.733-535A>C (intron variant)	G = 0.3115	T: OR = 1.25	Do et al., 2011

Ch, Chromosome. Data compiled from the GWAS catalog database, the dbSNP and the e!Ensembl (Sherry et al., 2001; Welter et al., 2014; Yates et al., 2016).

^*Denotes SNPs in 3'-UTR.